Stroke-Biomarkers.com

P01584

  • Synonyms:Interleukin-1 beta, Catabolin,
  • Biomarker name:IL1B
  • Gene name:IL1B
  • Gene id:3553
  • Genecards link:http://www.genecards.org/cgi-bin/carddisp.pl?gene=IL1B&search=IL-1beta
  • Biomarker function:Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Neurovascular unit:Microglia
  • Intracellular location:Secreted
  • Body fluids:Plasma, Serum, CSF
  • Prot-prot interactions:Unknown
  • Inductors:Unknown
  • Inhibitors:Unknown
  • Signaling pathway:Unknown
  • Biological process:Inflammatory response
  • Comments:-
  • Associations:Cytokines may contribute to both neurotoxicity and neuroprotection. IL1beta has been found elevated in ischemic stroke patients compared to mimics. No clear association has been found with aetiological classification of ischemic stroke
  • References:-

Source articles by endpoint

Etiologies
Endpoint Articles
CardioembolicTuttolomondo A, 2009;

Neurovascular Research Laboratory - Vall d'Hebron Research Institute (VHIR). 2013. Last update: 2017-03-28 12:25:27h.