Stroke-Biomarkers.com

778

  • Synonyms:HCY
  • Biomarker name:Homocysteine
  • Gene name:-
  • Gene id:-
  • Genecards link:http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=778
  • Biomarker function:Homocysteine is a non-protein aminoacid which must be biosynthesized from methionine.
  • Neurovascular unit:Unknown
  • Intracellular location:Unknown
  • Body fluids:Plasma, Serum, Urine
  • Prot-prot interactions:Unknown
  • Inductors:Unknown
  • Inhibitors:Unknown
  • Signaling pathway:Unknown
  • Biological process:
  • Comments:Hyperhomocysteinemia is related to endothelial injury [1], as it is involved in degradation and inhibition of formation of collagen, elastin and proteoglycans. Hyperhomocysteinemia can be treated with vitamins supplementation. Higher HCY levels in men and in the elderly.
  • Associations:Hyperhomocysteinemia is associated with death after stroke. Its association with long-term disability is not clear.No clear association has been found between homocysteine levels and aetiological classification of ischemic stroke
  • References:1. Jin L et al. Homocysteine induces endothelial dysfunction via inhibition of arginine transport. J Physiol Pharmacol. 2007, 58(2):191-206.

Source articles by endpoint

Prognosis
Endpoint Articles
DisabilityTu WJ, 2013;
ExitusTu WJ, 2013; Üstündağ M, 2010;
WorseningMen X, 2013;

Neurovascular Research Laboratory - Vall d'Hebron Research Institute (VHIR). 2013. Last update: 2017-03-28 12:25:27h.